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INCY

Incyte

NASDAQHealth CareBiotechnologySnapshot 2026-05-08

$98.56+0.81%
Close 2026-05-08 · 1-day change
The bottom line

As of May 8, 2026, INCY has a composite score of 25.4 and is labeled with a signal of "mild favorable." This score is influenced by a medium confidence level of 71.9 and reflects various factors, including a macro score of 31.5 and a valuation score of 74.1, which is considered inexpensive. The analysis is provisional, indicating that the information may be subject to change.

Composite +25as of 2026-05-08

Price

Daily closes from AlphaVantage. Earnings/event dots are placed inline.

Close 2026-05-08
Daily closes. Scroll over the chart to zoom; click a range to reset.
EarningsMaterial event

Factor signals

Read top-to-bottom: thesis (is this a strong company over a 1–3 year hold), watch flags (has something changed worth re-reading), and position context (how violent might the path be). Each pill is a parallel diagnostic — never aggregated into a single score.

L1

Thesis

is this a strong company over a 1–3 year hold?
F1 · Recent financial performance
weak
Bottom 10% of health care cohort
Why this rank
  • Direction share
    0.03
  • Slope (norm)
    -0.65
  • Bonus
    0.00
Operating income, last 4 quarters ($M)
92530444-1004
F2 · Value
cheap
Cheapest 30% of health care cohort
Why this rank
Price
$98.56
TTM EPS
$5.44
Earnings yield
5.5%
P/E (TTM)
18.1

Trailing four: 2024-Q3, 2025-Q1, 2025-Q2, 2025-Q3

F3 · Earnings quality
robust
Top 10% cash conversion in health care cohort
Why this rank
TTM NI ($M)
33
TTM CFO ($M)
335
CFO/NI
10.28
L2

Watch

has something changed worth re-reading?
F4 · Management stability
volatile
Bottom 20% activity in health care cohort· see deep-dive ↓
capital unfriendlyBottom 30% — net capital-unfriendly direction
Earnings setup · pre-print positioning
forward-looking
bullishEPS revised +3.4% / 30d, n=17for period ending 2026-06-30
Why this setup
Consensus revisions

EPS estimate $1.78 → $1.84 (+3.4% / 30d). 9 raised, 4 cut, 17 covering analysts.

Rating actions

0 upgrades, 0 downgrades / 30d, 4 maintained. 42% of analysts rate Buy.

Price target activity

1 PT revisions / 30d. Avg target -7.9% above current price.

Material events

1 positive, 0 negative / 30d. See F4 management tile for the event list.

Transition story with positive analyst positioning — often a turnaround setup.

F4 · Management deep-dive — recent events, stated priorities, guidance track record
2

Stated priorities

3 priorityies extracted from earnings transcripts (as of 2026-05-08).

  1. 1.Increase Hematology and Oncology salesgrowthbehind7% progress
    4/28: CEO: 'Hematology and Oncology portfolio net sales of $204 million, an increase of 116%.'
    Why this status

    Stated in 2 of last 2 quarters. Hematology and Oncology portfolio net sales increased from $94.44 million in 2025-Q1 to $204 million in 2026-Q1, a 116% increase. The trajectory shows strong growth in this segment, aligning with management's stated priority.

  2. 2.Manage R&D and SG&A expensescostbehind7% progress
    2/10: CEO: 'Total GAAP R&D and SG&A operating expenses of $3,495 to $3,675 million.'
    Why this status

    Stated in 2 of last 2 quarters. Total GAAP R&D and SG&A operating expenses are guided to be between $3,495 to $3,675 million for 2026. The expenses have been consistently managed, with R&D at $611.4 million and SG&A at $390.4 million in 2025-Q4, indicating a focus on cost management.

  3. 3.Achieve product revenue targetsgrowthbehind7% progress
    2/10: CEO: 'Total net product revenue guidance of $4.77 to $4.94 billion.'
    Why this status

    Stated in 2 of last 2 quarters. Total net product revenue for 2025 was $4.35 billion, with guidance for 2026 set at $4.77 to $4.94 billion. The company is focused on achieving these targets, with a 20% increase in total net sales in 2026-Q1 compared to 2025-Q1, indicating progress towards the goal.

3

Guidance track record

Insufficient guidance history for this ticker.

L3

Position context

how violent might the path be while I hold it?
Risk profile · realized
backward-looking
moderateworst 12m loss −18%, typical day ±1.2%
Why this risk level

Recent vol — 30d annualized 28%; 252d 32%.

Drawdown — Max 1y −18%. Bad day move −3%.

Beta to sector ETF (XLV) 0.94 over 1y.

Liquidity — score 100/100.

Sub-scores — vol 46/100, drawdown 63/100, beta 94/100, earnings vol .

Sector regime
headwind-15.1%sector vs S&P 500, 60d

via XLV

Tailwind = sector leading the S&P 500; headwind = trailing. Both can be constructive — historically, headwind regimes have averaged stronger forward returns than tailwind.

AI cycle regime · market-wide
2-axis classifier
HeatingManiaSquallCrisisEarnings →Mood ↑
HeatingE +0.13 · M +0.71
Single-axisCHASEz +2.97+1.285d

Context label only — describes the market state (e.g. real bear vs narrative panic, healthy uptrend vs late-stage froth). It is not a per-ticker buy/sell signal and does not predict factor performance.

Not investment advice. As of 2026-05-08.

3

What changed

The most important moves since the prior daily snapshot.

  1. No material changes since the prior snapshot.

No material changes since the prior snapshot.

as of 2026-05-08

4

Management scorecard

How management runs the business — capital, margins, balance sheet, and how reliably they guide and deliver.

Composite47.7 / 100
Capital allocation59
Earnings discipline35
Margin discipline30
Balance sheet54
Guidance credibility
Post-call reaction53
as of 2026-05-08
4

What management is focused on

Priorities management has stated in recent disclosures, with status and evidence drawn from earnings calls, filings, and press releases.

  • #1

    Increase Hematology and Oncology sales

    GrowthNew since 2026-05-04

    Focus on boosting sales in the Hematology and Oncology segment.

    Behind

    Stated in 2 of last 2 quarters. Hematology and Oncology portfolio net sales increased from $94.44 million in 2025-Q1 to $204 million in 2026-Q1, a 116% increase. The trajectory shows strong growth in this segment, aligning with management's stated priority.

    7%
    CEO/CFO:CEO: 'Hematology and Oncology portfolio net sales of $204 million, an increase of 116%.'
    Press releaseSource dated 2026-04-28Stated 2 of last 8 quartersFirst seen 2026-05-04
    Show history (2)
    • 2026-Q1Press release

      CEO: 'Hematology and Oncology portfolio net sales of $204 million, an increase of 116%.

    • 2025-Q4Press release

      CEO: 'Total net product revenue for Hematology and Oncology increased.'

  • #2

    Manage R&D and SG&A expenses

    CostNew since 2026-05-04

    Maintain control over R&D and SG&A expenses to optimize financial performance.

    Behind

    Stated in 2 of last 2 quarters. Total GAAP R&D and SG&A operating expenses are guided to be between $3,495 to $3,675 million for 2026. The expenses have been consistently managed, with R&D at $611.4 million and SG&A at $390.4 million in 2025-Q4, indicating a focus on cost management.

    7%
    CEO/CFO:CEO: 'Total GAAP R&D and SG&A operating expenses of $3,495 to $3,675 million.'
    Press releaseSource dated 2026-02-10Stated 2 of last 8 quartersFirst seen 2026-05-04
    Show history (2)
    • 2026-Q1Press release

      CEO: 'Total GAAP R&D and SG&A operating expenses of $3,495 to $3,675 million.'

    • 2025-Q4Press release

      CEO: 'R&D expenses were $611.4 million, SG&A expenses were $390.4 million.'

  • #3

    Achieve product revenue targets

    GrowthNew since 2026-05-04

    Strive to meet or exceed product revenue targets across key segments.

    Behind

    Stated in 2 of last 2 quarters. Total net product revenue for 2025 was $4.35 billion, with guidance for 2026 set at $4.77 to $4.94 billion. The company is focused on achieving these targets, with a 20% increase in total net sales in 2026-Q1 compared to 2025-Q1, indicating progress towards the goal.

    7%
    CEO/CFO:CEO: 'Total net product revenue guidance of $4.77 to $4.94 billion.'
    Press releaseSource dated 2026-02-10Stated 2 of last 8 quartersFirst seen 2026-05-04
    Show history (2)
    • 2026-Q1Press release

      CEO: 'Total net product revenue guidance of $4.77 to $4.94 billion.'

    • 2025-Q4Press release

      CEO: 'Total net product revenue for the full year of 2025 was $4.35 billion.'

as of 2026-05-08
5

How this stock is priced

Two ways to read price: against peers in the same business, and against the company's own history.

Compared to peers
78higher = cheaper

Looks cheaper than most peers in the same business.

Compared to its own history
90higher = cheaper

Cheaper than its own typical valuation.

P/E
13.1x
EV/EBITDA
11.5x
FCF yield
7.4%

P/E over the last 5 years

40 monthly points
inexpensiveas of 2026-05-08
7

How this compares

A side-by-side read on composite, valuation, and risk versus peers.

StockCompositeValuationRisk
INCY
Incyte
+25inexpensivemoderate
LLY
Lilly (Eli)
+21fullmoderate
JNJ
Johnson & Johnson
+18fulllow
ABBV
AbbVie
+12fairlow
UNH
UnitedHealth Group
+24fairelevated
8

Risk — how this stock moves

What a normal day looks like, what a bad day looks like, and the worst the last year has thrown at it.

A typical day
How much price usually moves either way.
1.2%
A bad day (95th %ile)
A rough but not unusual down day.
-2.7%
Worst 12-month loss
Deepest peak-to-trough drop in the last year.
-18.3%
Earnings-day move
How much price usually moves on earnings day.
moderateas of 2026-05-08
9

What could change this view

Conditional scenarios — if X happens, the score would shift by about Y points. These are not predictions.

Upside triggers
  • If health_care sector trend rises from +0.06 into 'improving' (>= +0.20)+5.0 pts
  • If next-quarter guidance is raised (currently NEW as of 2026-04-28)+4.0 pts
Downside triggers
  • If next-quarter guidance is cut (currently NEW as of 2026-04-28)-8.0 pts
  • If labor state reverses from -0.31 (negative) to +0.31 (positive)-6.8 pts
  • If health_care sector trend falls from +0.06 into 'weakening' (<= -0.20)-5.0 pts
10

Material updates

Recent SEC 8-K filings ranked by likely impact, confidence, and recency.

  1. 2026-04-2810d agoItem 2.02

    Results of Operations and Financial Condition. On April 28, 2026 , Incyte Corporation issued a press release announcing financial results for its first fiscal quarter ended March 31, 2026. The full text of the press release is furnished as Exhibit 99.1.

    earnings preannouncementpositivescore 57
  2. 2026-03-301mo agoItem 5.02

    Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. On March 26, 2026, Susanne Schaffert notified Incyte Corporation (the “Company”) that she was resigning from the Company’s Board of Directors (the “Board”), effective as of April 15, 2026. The resignation of Dr. Schaffert, who has been a member of the Company’s Board since 2022, was not the result of any disagreement with the Company on any matter…

    executive changeneutralscore 23
  3. 2026-03-261mo agoItem 5.02

    Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers. On March 25, 2026, Incyte Corporation (the “Company”) announced title changes for certain current members of its executive leadership team, effective immediately. Pablo J. Cagnoni’s title was changed to President, Incyte and Global Head of Research and Development; Steven H. Stein’s title was changed to Executive Vice President, Chief Medical Offic…

    executive changeneutralscore 21
  4. 2026-03-062mo agoItem 8.01

    Other Events. On February 27, 2026, the U.S. Food and Drug Administration (“FDA”) issued a Complete Response Letter (“CRL”) for the supplemental Biologics License Application (“sBLA”) for Zynyz® (retifanlimab-dlwr) injection (375mg) for an additional indication for the treatment of adult patients with metastatic non-small cell lung cancer (“NSCLC”) in combination with platinum-based chemotherapy. The sBLA was supported by positive efficacy and safety data from the Phase 3 POD1UM-304 trial ann…

    legal regulatorynegativescore 12
  5. 2026-02-102mo agoItem 2.02

    Results of Operations and Financial Condition. On February 10, 2026, Incyte Corporation issued a press release announcing financial results for its fourth fiscal quarter and year ended December 31, 2025. The full text of the press release is furnished as Exhibit 99.1.

    earnings preannouncementneutralscore 9
11

Score history

The composite score, snapshot by snapshot. The dotted line at zero separates leaning-positive from leaning-negative.

60 snapshots
Data freshness · As of 2026-05-08 · Macro 2026-05-08 · Sector 2026-05-07 · Fundamentals 2026-02-10 · Price 2026-05-07 · Generated 2026-05-08 · Spec 2.3

Not investment advice. Scores describe historical and current data; they are not forecasts of future returns. Consult a licensed advisor before making investment decisions.