Results of Operations and Financial Condition. On May 12, 2026, Rezolute, Inc. issued a press release announcing its financial results for the third quarter ended March 31, 2026. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that sec…

Results of Operations and Financial Condition. On February 12, 2026, Rezolute, Inc. issued a press release announcing its financial results for the second quarter ended December 31, 2025. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of…

Results of Operations and Financial Condition. On November 6, 2025, Rezolute, Inc. issued a press release announcing its financial results for the first quarter ended September 30, 2025. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of…

Entry Into Material Definitive Agreement

Termination of a Material Definitive Agreement. On October17, 2025, the Company delivered written notice to Jefferies LLC indicating that it is terminating the Open Market Sale Agreement by and between the Company and Jefferies LLC, dated November 14, 2023, effective as of October 24, 2025. The Company filed with the SEC a prospectus supplement, which formed a part of the Registration Statement on Form S-3 (File No. 333-275562), declared effective by the SEC on November 29, 2023, relating to…

Amendments to employment agreements for gross-up payments in case of a change of control event.

Results of Operations and Financial Condition. On September 17, 2025, Rezolute, Inc. issued a press release announcing its financial results for the fourth quarter and fiscal year ended June 30, 2025. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the…

Chief Commercial Officer — Sunil Karnawat: Dr. Sunil Karnawat was hired as the new Chief Commercial Officer.

Entry into a Material Definitive Agreement.

Other Events. As previously reported in the Company’s Current Report on Form 8-K, filed with the Securities and Exchange Commission on April 23, 2025, certain insiders of the Company agreed to purchase up to $10,000,000 of shares of Common Stock at a price of $3.25 per share in a private placement (the “ Private Placement ”). On June 13, 2025, pursuant to the terms of a Securities Purchase Agreement, by and among the Company and certain investors (collectively, the “ Investors ”), the Company…

member of the Compensation Committee — Mr. Harris: Mr. Harris was appointed to the Compensation Committee.

Unregistered Sales of Equity Securities. The disclosures set forth below in

Results of Operations and Financial Condition. On May 13, 2025, Rezolute, Inc. issued a press release announcing its financial results for the third quarter ended March 31, 2025. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that sec…

Other Events. Private Placement In a transaction separate from the Registered Direct Offering, certain insiders of the Company have agreed to purchase up to $10,000,000 of shares of Common Stock at a price of $3.25 per share, which reflects the Registered Direct Offering price (the “ Private Placement ”) which exceeds the definition of market value for Nasdaq Listing Rule 5635(c) purposes. The shares of Common Stock offered in the Private Placement were offered pursuant to an exemption from r…

Entry into a Material Definitive Agreement. Registered Direct Offering On April 23, 2025, Rezolute, Inc. (the “ Company ”) entered into an underwriting agreement (the “ Underwriting Agreement ”) with Guggenheim Securities, LLC (“ Guggenheim Securities ”), as representative of the underwriters listed therein (the “ Underwriters ”), relating to the issuance and sale in a registered direct offering (the “ Registered Direct Offering ”) by the Company of (i) 20,786,923 shares (the “ Shares ”) of t…

Unregistered Sales of Equity Securities. The information under

Director — Erik Harris: Erik Harris was elected to the Board of Directors.

Results of Operations and Financial Condition. On February 12, 2025, Rezolute, Inc. issued a press release announcing its financial results for the second quarter ended December 31, 2024. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of…

Results of Operations and Financial Condition. On November 7, 2024, Rezolute, Inc. issued a press release announcing its financial results for the first quarter ended September 30, 2024. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of…

Results of Operations and Financial Condition. On September 19, 2024, Rezolute, Inc. issued a press release announcing its financial results for the fourth quarter and fiscal year ended June 30, 2024. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the…

Unregistered Sales of Equity Securities. The information under

Entry into a Material Definitive Agreement. On June 25, 2024, the Company entered into a securities purchase agreement (the “Securities Purchase Agreement”) with certain purchasers as identified therein (the “Purchasers”) relating to a private placement (the “Private Placement”), pursuant to which the Company agreed to sell to the Purchasers 1,500,000 shares of Common Stock (“Private Shares”) at a purchase price of $4.00 per share, which represents a premium to the Nasdaq consolidated closing…

Entry into a Material Definitive Agreement. On June 13, 2024, Rezolute, Inc. (the “Company”) entered into an underwriting agreement (the “Underwriting Agreement”) with Jefferies LLC and Cantor Fitzgerald & Co., as representatives of the underwriters listed therein (the “Underwriters”), relating to the issuance and sale in an underwritten public offering (the “Public Offering”) by the Company of (i) 11,250,000 shares (the “Shares”) of the Company’s common stock, par value $0.001 per share (the…

Results of Operations and Financial Condition. On May 15, 2024, Rezolute, Inc. issued a press release announcing its financial results for the third quarter ended March 31, 2024. A copy of this press release is attached hereto as Exhibit 99.1. The information in this Current Report on Form 8-K, including Exhibit 99.1, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that sec…

Changes in Registrant’s Certifying Accountants. (a) Termination of Independent Registered Public Accounting Firm On March 8, 2024, the Company dismissed Plante & Moran, PLLC (“Plante Moran”) as its independent registered public accounting firm. The Company’s Audit Committee (the “Audit Committee”) unanimously approved the decision to dismiss Plante Moran. Plante Moran performed audits of the Company's consolidated financial statements for the years ended June 30, 2023 and 2022. Plante Moran’s…