Changes in Control of Registrant. The information set forth in the Introductory Note and in Items 2.01, 3.01, 3.03, 5.02 and 5.03 of this Current Report on Form 8-K is incorporated by reference in this

Regulation FD Disclosure. On October 6, 2026, the Company issued a press release announcing the closing of the Merger. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference. The information included in this Item 7.01, including Exhibit 99.1 attached hereto, is being furnished and shall not be deemed to be filed for purposes of Section 18 of the Exchange Act, or otherwise subject to the liabilities of that section, nor shall it be deemed incorpo…

Director: The filing describes a merger where the entire board was replaced and a new President was appointed, which is a structural change rather than a routine departure or simple promotion.

In connection with the completion of the Merger, on October 6, 2026, the Company (i) notified the Nasdaq Stock Market LLC (“ Nasdaq ”) that the Merger has been completed and (ii) submitted a request to Nasdaq for Nasdaq to cease trading of the Company Common Shares on Nasdaq and to suspend the listing of the Company Common Shares and to file with the SEC an application on Form 25 to delist the Company Common Shares from Nasdaq and deregister the Company Common Shares under Section 12(b) of th…

As a result of the Merger, each Company Common Share that was issued and outstanding immediately prior to the Effective Time (except for the Cancelled Shares and the Dissenting Shares) was automatically cancelled and converted, at the Effective Time, into the right to receive the Merger Consideration. Accordingly, at the Effective Time, the holders of such Company Common Shares ceased to have any rights as shareholders of the Company, other than the right to receive the Merger Consideration.

At the Effective Time, in accordance with the terms set forth in the Merger Agreement, each issued and outstanding share of common stock of the Company, par value $0.001 per share (the “ Company Common Shares ”) (other than (a) Company Common Shares held by the Company as treasury shares or owned by Parent, Merger Sub or any other subsidiary of Parent immediately prior to the Effective Time (the “ Cancelled Shares ”) and (b) Company Common Shares held by shareholders who did not vote in favor…

Other Events As previously disclosed in the Company’s Current Report on Form 8-K filed with the SEC on August 13, 2026, the closing of the Merger remains subject to the satisfaction or waiver of other customary conditions including without limitation, the receipt of certain regulatory approvals in France. Forward-Looking Statements This communication contains forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. An…

Other Events. As previously announced, on June 16, 2026, Simulations Plus, Inc., a California corporation (the “ Company ”), entered into an Agreement and Plan of Merger (the “ Merger Agreement ”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company (“ Parent ”) and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“ Merger Sub ”), pursuant to which Merger Sub will merge with and into the Company (t…

Results of Operations and Financial Condition On July 9, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its third quarter ended May 31, 2026. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Entry Into a Material Definitive Agreement. Agreement and Plan of Merger On June 15, 2026, Simulations Plus, Inc., a California corporation (the “ Company ”), entered into an Agreement and Plan of Merger (the “ Merger Agreement ”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company and an affiliate of Altaris, LLC (“ Parent ”) and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“ Merger Sub ”), p…

The filing describes a transaction bonus program for certain employees, including executive officers, contingent upon the completion of a merger.

Regulation FD Disclosure. On June 16, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing the execution of an Agreement and Plan of Merger (the “Merger Agreement”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company and an affiliate of Altaris, LLC (“Parent”), and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“Merger Sub”), pursuant to which…

Results of Operations and Financial Condition On April 9, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its second quarter ended February 28, 2026. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

The excerpt is incomplete and does not provide sufficient information to determine the nature of the event.

Results of Operations and Financial Condition On January 8, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its first quarter ended November 30, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

The information provided is incomplete and does not specify any specific movement or event.

Entry into a Material Definitive Agreement. On December 2, 2025, Simulations Plus, Inc. (the “Company”) entered into amended and restated employment agreements (each, an “Agreement,” and collectively, the “Agreements”) with (i) Shawn O’Connor, the Company’s Chief Executive Officer; (ii) Will Frederick, the Company’s Executive Vice President and Chief Financial Officer; (iii) John DiBella, the Company’s Chief Revenue Officer; (iv) Jill Fiedler-Kelly, the Company’s President, Service Solutions;…

Results of Operations and Financial Condition On December 1, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its fourth quarter and fiscal year ended August 31, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition,” on October 22, 2025, the Company issued the Press Release announcing certain preliminary operational results for its fourth fiscal quarter ended August 31, 2025 and providing its guidance and estimates for the fiscal year ending August 31, 2026. A copy of such Press Release is attached to this Report as Exhibit 99.1. In accordance with General Instructions B.2 of Form 8-K, the information in Items 2.02 and 7.01 of this Report and the Exhibit 99.…

Changes in Registrant’s Certifying Accountant (a) Termination of the Company’s independent registered public accounting firm. On July 9, 2025, the Audit Committee of the Board of Directors (the “Audit Committee”) of Simulations Plus, Inc. (the “Company”) approved the dismissal of Grant Thornton LLP (“Grant Thornton”) as the Company’s independent public accounting firm. Following discussions between the Company and Grant Thornton, the Audit Committee determined that a change in auditors would…

Results of Operations and Financial Condition On July 14, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its third quarter ended May 31, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition On June 11, 2025 Simulations Plus, Inc. (the “Company”) issued a press release announcing certain preliminary operational results for its third fiscal quarter and updating its guidance ranges for the fiscal year ending August 31, 2025. A copy of such press release is attached hereto as Exhibit 99.1.

Costs Associated with Exit or Disposal Activities On the Effective Date, the Company restructured its operations to reduce its workforce and implemented focused cost reductions across the Company to enhance its operational efficiency and reduce operating expenses. The reduction in workforce will decrease overall headcount by approximately 23 employees, which represents approximately 10% of full-time employees as of the Effective Date. The Company estimates that it will incur approximately $0.…

Chief Revenue Officer — Daniel Szot: Mr. Szot's separation from the Company was mutually agreed upon, allowing for a smooth transition as he pursues other opportunities.

Changes in Registrant’s Certifying Accountant (a) Former Independent Registered Public Accounting Firm. The Audit Committee of the Board of Directors (the “Audit Committee”) of Simulations Plus, Inc. (the “Company”) has completed a competitive process to review the appointment of the Company’s independent registered public accounting firm for the fiscal year ending August 31, 2025. The Audit Committee approved the dismissal of Rose, Snyder & Jacobs LLC (“RSJ”) as the Company’s independent reg…