Other Events As previously disclosed in the Company’s Current Report on Form 8-K filed with the SEC on August 13, 2026, the closing of the Merger remains subject to the satisfaction or waiver of other customary conditions including without limitation, the receipt of certain regulatory approvals in France. Forward-Looking Statements This communication contains forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. An…

Other Events. As previously announced, on June 16, 2026, Simulations Plus, Inc., a California corporation (the “ Company ”), entered into an Agreement and Plan of Merger (the “ Merger Agreement ”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company (“ Parent ”) and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“ Merger Sub ”), pursuant to which Merger Sub will merge with and into the Company (t…

Results of Operations and Financial Condition On July 9, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its third quarter ended May 31, 2026. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Entry Into a Material Definitive Agreement. Agreement and Plan of Merger On June 15, 2026, Simulations Plus, Inc., a California corporation (the “ Company ”), entered into an Agreement and Plan of Merger (the “ Merger Agreement ”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company and an affiliate of Altaris, LLC (“ Parent ”) and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“ Merger Sub ”), p…

The filing describes a transaction bonus program for certain employees, including executive officers, contingent upon the completion of a merger.

Regulation FD Disclosure. On June 16, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing the execution of an Agreement and Plan of Merger (the “Merger Agreement”) by and among the Company, SP Evolution HoldCo II, LLC, a Delaware limited liability company and an affiliate of Altaris, LLC (“Parent”), and SP Evolution BidCo II, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“Merger Sub”), pursuant to which…

Results of Operations and Financial Condition On April 9, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its second quarter ended February 28, 2026. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

The excerpt is incomplete and does not provide sufficient information to determine the nature of the event.

Results of Operations and Financial Condition On January 8, 2026, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its first quarter ended November 30, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

The information provided is incomplete and does not specify any specific movement or event.

Entry into a Material Definitive Agreement. On December 2, 2025, Simulations Plus, Inc. (the “Company”) entered into amended and restated employment agreements (each, an “Agreement,” and collectively, the “Agreements”) with (i) Shawn O’Connor, the Company’s Chief Executive Officer; (ii) Will Frederick, the Company’s Executive Vice President and Chief Financial Officer; (iii) John DiBella, the Company’s Chief Revenue Officer; (iv) Jill Fiedler-Kelly, the Company’s President, Service Solutions;…

Results of Operations and Financial Condition On December 1, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its fourth quarter and fiscal year ended August 31, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition,” on October 22, 2025, the Company issued the Press Release announcing certain preliminary operational results for its fourth fiscal quarter ended August 31, 2025 and providing its guidance and estimates for the fiscal year ending August 31, 2026. A copy of such Press Release is attached to this Report as Exhibit 99.1. In accordance with General Instructions B.2 of Form 8-K, the information in Items 2.02 and 7.01 of this Report and the Exhibit 99.…

Changes in Registrant’s Certifying Accountant (a) Termination of the Company’s independent registered public accounting firm. On July 9, 2025, the Audit Committee of the Board of Directors (the “Audit Committee”) of Simulations Plus, Inc. (the “Company”) approved the dismissal of Grant Thornton LLP (“Grant Thornton”) as the Company’s independent public accounting firm. Following discussions between the Company and Grant Thornton, the Audit Committee determined that a change in auditors would…

Results of Operations and Financial Condition On July 14, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its third quarter ended May 31, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition On June 11, 2025 Simulations Plus, Inc. (the “Company”) issued a press release announcing certain preliminary operational results for its third fiscal quarter and updating its guidance ranges for the fiscal year ending August 31, 2025. A copy of such press release is attached hereto as Exhibit 99.1.

Costs Associated with Exit or Disposal Activities On the Effective Date, the Company restructured its operations to reduce its workforce and implemented focused cost reductions across the Company to enhance its operational efficiency and reduce operating expenses. The reduction in workforce will decrease overall headcount by approximately 23 employees, which represents approximately 10% of full-time employees as of the Effective Date. The Company estimates that it will incur approximately $0.…

Chief Revenue Officer — Daniel Szot: Mr. Szot's separation from the Company was mutually agreed upon, allowing for a smooth transition as he pursues other opportunities.

Changes in Registrant’s Certifying Accountant (a) Former Independent Registered Public Accounting Firm. The Audit Committee of the Board of Directors (the “Audit Committee”) of Simulations Plus, Inc. (the “Company”) has completed a competitive process to review the appointment of the Company’s independent registered public accounting firm for the fiscal year ending August 31, 2025. The Audit Committee approved the dismissal of Rose, Snyder & Jacobs LLC (“RSJ”) as the Company’s independent reg…

Results of Operations and Financial Condition On April 3, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its second quarter ended February 28, 2025. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition On January 7, 2025, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its first quarter ended November 30, 2024. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Results of Operations and Financial Condition On October 23, 2024, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its fourth quarter and fiscal year ended August 31, 2024. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

President, Quantitative Systems Pharmacology — Dr. Brett Howell, Ph.D.: Dr. Howell departed the Company with a severance package.

Results of Operations and Financial Condition On July 2, 2024, Simulations Plus, Inc., a California corporation (the “Company”), issued a press release announcing financial results for its third quarter of fiscal year 2024 ended May 31, 2024. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K (this “Report”).

Entry into a Material Definitive Agreement. On June 11, 2024, Simulations Plus, Inc. (the “Company”) entered into a Stock Purchase Agreement, by and among the Company, Pro-ficiency Holdings, Inc. (“Pro-ficiency”), each of the stockholders of Pro-ficiency (collectively, the “Sellers”) and WRYP Stockholders Services, LLC, solely in its capacity as the Sellers’ Representative (the “Purchase Agreement”). Pursuant to the Purchase Agreement, at closing on June 11, 2024 (the “Closing”), the Company…