Results of Operations and Financial Condition. On August 11, 2026, Spectral AI, Inc. (the “Company”) reported its financial results for the quarter ended June 30, 2026. Additionally, the Company hosted a conference call on August 11, 2026, at 5:00 pm Eastern Time with financial analysts to discuss the Company’s financial results and other business matters. This event will be available for replay on the Company’s website: https://investors.spectral-ai.com/news-events/events.

Chief Commercial Officer — Darcy Bajko: The company has hired a new Chief Commercial Officer with extensive experience in commercialization and market development.

Chief Executive Officer — Vincent S. Capone: Mr. Capone was appointed as Chief Executive Officer and received a new employment agreement with compensation details.

Chief Financial Officer — David McGuire: The company hired a new Chief Financial Officer with extensive experience.

Results of Operations and Financial Condition. On March 24, 2026, Spectral AI, Inc. (the “Company”) reported its financial results for the quarter and year ended December 31, 2025. Additionally, the Company hosted a conference call on March 24, 2026, at 5:00 pm Eastern Time with financial analysts to discuss the Company’s financial results and other business matters. This event will be available for replay on the Company’s website: https://investors.spectral-ai.com/news-events/events.

Chief Executive Officer — Vincent S. Capone: Mr. Capone was promoted from Chief Financial Officer and General Counsel to Chief Executive Officer.

Chief Commercial Officer — Mr. Jeremiah Sparks: Mr. Jeremiah Sparks is leaving the company to pursue other opportunities.

Director — Colin Bristow: Colin Bristow resigned as a director of the company.

Entry into a Material Definitive Agreement. Securities Purchase Agreement On October 22, 2025, Spectral AI, Inc. (the “Company”) entered into a securities purchase agreement (the “Purchase Agreement”) with a certain investor (the “Investor”) for the sale of 3,065,000 shares (the “Shares”) of the Company’s common stock, par value $0.0001 per share (“Common Stock”), at an offering price of $1.90 per Share (such transaction, the “Offering”). The sale and issuance of the Shares is being made purs…

of this Current Report on Form 8-K. The Warrants and Pre-Funded Warrants being sold to the Investor will be issued in reliance on the exemptions provided in Section 4(a)(2) under the Securities Act. Accordingly, the Investor may only resell the Warrants, Pre-Funded Warrants and the shares of Common Stock issuable upon exercise of the Warrants and Pre-Funded Warrants, pursuant to an effective registration statement under the Securities Act covering the resale of such shares of Common Stock, an…

to this Current Report on Form 8-K, and in Exhibit 99.1 furnished herewith, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing. This report cont…

Additionally, the Company hosted a conference call on August 12, 2025, at 5:00 pm Eastern Time with financial analysts to discuss the Company’s financial results and other business matters. The event will be available for replay on the Company’s website: https://investors.spectral-ai.com/news-events/events. As provided in General Instruction B.2 of Form 8-K, the information and exhibits provided pursuant to this

Changes in Registrant’s Certifying Accountant (a) On May 29, 2025, Spectral AI, Inc. (the “Company”) dismissed KPMG LLP (“KPMG”) as the Company’s independent registered public accounting firm, effective immediately. The Company’s Audit Committee unanimously voted in favor of dismissing KPMG as the Company’s independent auditors. The Company’s Board of Directors (the “Board”) ratified such recommendation. KPMG has served as the Company’s independent registered public accounting firm since 2021…

Chief Operating Officer (COO) — Stanley Micek: Stanley Micek was promoted to Chief Operating Officer from his previous role as Interim COO.

Additionally, the Company hosted a conference call on May 13, 2025, at 5:00 pm Eastern Time with financial analysts to discuss the Company’s financial results and other business matters. The event will be available for replay on the Company’s website: https://investors.spectral-ai.com/news-events/events. As provided in General Instruction B.2 of Form 8-K, the information and exhibits provided pursuant to this

Chief Financial Officer — Vincent Capone: Amendment to employment agreement and compensation adjustments for the Chief Financial Officer.

Additionally, the Company hosted a conference call on March 27, 2025, at 5:00 pm Eastern Time with financial analysts to discuss the Company’s financial results and other business matters. The event will be available for replay on the Company’s website: https://investors.spectral-ai.com/news-events/events. As provided in General Instruction B.2 of Form 8-K, the information and exhibits provided pursuant to this

Creation of a Direct Financial Obligation or an Obligation under an Off-Balance As described in

of this Current Report on Form 8-K. The Warrants being sold to the Investors will be issued in reliance on the exemptions provided in Section 4(a)(2) under the Securities Act. Accordingly, the Investors may only resell the Warrants and the Warrant Shares, pursuant to an effective registration statement under the Securities Act covering the resale of the Warrant Shares, an exemption under Rule 144 under the Securities Act or another applicable exemption under the Securities Act and any applica…

to this Current Report on Form 8-K, and in Exhibit 99.1 furnished herewith, shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall such information be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing. This report cont…

Entry into a Material Definitive Agreement. Securities Purchase Agreement On March 21, 2025, Spectral AI, Inc. (the “Company”) entered into securities purchase agreements (the “Purchase Agreements”) with certain investors in the United States and the United Kingdom (the Investors from the United Kingdom, the “UK Investors,” and collectively, the “Investors”) for the sale of an aggregate of 2,076,923 shares (the “Shares”) of the Company’s common stock, par value $0.0001 per share (“Common Stoc…

Entry into a Material Definitive Agreement. On November 18, 2024, Spectral AI, Inc. (the “Company”) entered into a securities purchase agreement (the “Purchase Agreement”) with an investor (the “Investor”) for the sale of up to $5,000,000 in shares of common stock of the Company, par value 0.0001 per share (“Common Stock”). On December 12, 2024, the Investor delivered a purchase notice under the Purchase Agreement for the purchase of 500,000 shares of Common Stock (the “Shares”), at an offeri…

Entry into a Material Definitive Agreement. On November 18, 2024, Spectral AI, Inc. (the “Company”) entered into a securities purchase agreement (the “Purchase Agreement”) with an investor (the “Investor”) for the sale of (i) 920,000 shares (“Shares”) of our common stock, par value $0.0001 per share (“Common Stock”), at an offering price of $1.38 per share, and (ii) pre-funded warrants to purchase up to 725,000 shares of Common Stock (the “Pre-Funded Warrants”) at an offering price of $1.38 p…

Entry into a Material Definitive Agreement. Securities Purchase Agreement On December 6, 2024, Spectral AI, Inc. (the “Company”) entered into a securities purchase agreement (the “Purchase Agreement”) with certain investors in the United Kingdom (the “Investors”) for the sale of 270,900 shares (the “Shares”) of our common stock, par value $0.0001 per share (“Common Stock”), at an offering price of $1.66 per Share (such transaction, the “Offering”). The sale and issuance of the Shares is being…

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing. As previously disclosed, on June 3, 2024, Spectral AI, Inc. (the “Company”) received a letter from the Listing Qualifications Staff of The Nasdaq Stock Market LLC (“Nasdaq”) indicating that, based upon the closing bid price of the Company’s common stock, par value $0.0001 per share (“Common Stock”), for the previous 30 consecutive business days, the Company was not in compliance with the requi…