of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Approval of an amendment to the stock purchase plan, which is a routine corporate action.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Results of Operations and Financial Condition. On April 9, 2026, Orthofix Medical Inc. (the “Company”) issued a news release announcing, among other things, preliminary net sales results for the fiscal quarter ended March 31, 2026. A copy of the news release is furnished as Exhibit 99.1 and attached hereto. The information furnished in this Item 2.02, including the exhibit furnished herewith as Exhibit 99.1, will not be treated as “filed” for the purposes of Section 18 of the Securities Excha…

President, Global Spine — Max Reinhardt: Mr. Reinhardt is leaving the company as an executive and employee.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Entry into a Material Definitive Agreement. On April 1, 2025, Orthofix Medical Inc. (the “Company”) became tenant under a new lease governing its Carlsbad, California office location (5770 Armada Drive) (the “New Lease”), which became effective on such date. The Company had previously been tenant pursuant to a prior sublease with respect to such location (which is filed as Exhibit 10.12 to the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024), which sublease te…

Termination of a Material Definitive Agreement. The disclosure contained in

Director — Vickie Capps: Ms. Vickie Capps was appointed as a new independent director.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. The disclosure set forth under “

Entry into a Material Definitive Agreement. On November 7, 2024, the Company, as borrower, and its U.S. subsidiaries entered into a $275 million secured credit agreement (the “New Credit Agreement”) with Oxford Finance LLC, as administrative agent and as collateral agent (“Oxford”) and certain lenders party thereto, including Oxford and K2 Healthventures LLC. Certain of the Company’s foreign subsidiaries are expected to join the New Credit Agreement as guarantors shortly after the signing dat…

Termination of a Material Definitive Agreement. On the Effective Date, the Company repaid all amounts outstanding under and terminated its Financing Agreement, dated November 6, 2023, with Blue Torch Finance, LLC and certain lender parties thereto.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

President, Global Orthopedics — Kimberley A. Elting: Kimberley A. Elting is departing as President, Global Orthopedics.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Director — Stuart M. Essig, Ph.D., James F. Hinrichs, Catherine M. Burzik: Three directors have decided not to stand for re-election at the upcoming annual meeting.

of this report. Discussion of Non-GAAP Financial Measures In addition to using standard measures of performance and liquidity that are recognized in accordance with accounting principles generally accepted in the United States of America ("GAAP"), the Company uses additional financial measures excluding certain GAAP items ("non-GAAP measures"), such as: Constant Currency Constant currency is a non-GAAP measure, which the Company calculates by using foreign currency rates from the comparable,…

Results of Operations and Financial Condition. On January 9, 2024, Orthofix Medical Inc. (the “Company”) issued a news release announcing, among other things, its preliminary unaudited net sales for the fiscal quarter and year ended December 31, 2023. A copy of the press release is furnished herewith as Exhibit 99.1 and attached hereto. The information furnished in this Item 2.02, including the exhibit furnished herewith as Exhibit 99.1, will not be treated as “filed” for the purposes of Sect…

President and Chief Executive Officer — Massimo Calafiore: Massimo Calafiore was appointed as President and Chief Executive Officer, expanding his role within the company.

Entry into a Material Definitive Agreement. Cooperation Agreement On December 11, 2023, Orthofix Medical Inc. (the “Company”) entered into a cooperation agreement (the “Cooperation Agreement”) with Engine Capital, L.P., Engine Jet Capital, L.P., Engine Lift Capital, LP, Engine Capital Management, LP, Engine Capital Management GP, LLC, Engine Investments, LLC and Engine Investments II, LLC and Arnaud Ajdler (collectively, the “Engine Group”). Pursuant to the Cooperation Agreement, the Board of…