Results of Operations and Financial Condition. On August 5, 2026, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the second quarter ended June 30, 2026. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1…

Regulation FD Disclosure. In connection with the completion of Eli Lilly and Company’s acquisition of Ajax Therapeutics, Inc. (“Ajax”), a company co-founded by Schrödinger, Inc. (the “Company”), the Company received a cash payment of approximately $57 million. The Company is also eligible to receive additional cash payments upon the achievement by Ajax of specified clinical and regulatory milestones. The information in this Current Report on Form 8-K is being furnished and shall not be deemed…

The filing describes an amendment to the equity incentive plan, not a management change.

Chief Commercial Officer, Global Head of Software Sales and Marketing — Mannix Aklian: Mr. Aklian's separation from the Company with a severance package.

is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such a filing. Cautionary Note Regarding Forward-Looking Statements This Current Report on Form 8-K cont…

Chief Commercial Officer, Global Head of Software Sales and Marketing — Mannix Aklian: Mannix Aklian ceased to serve as Chief Commercial Officer, Global Head of Software Sales and Marketing.

Results of Operations and Financial Condition. On May 5, 2026, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the first quarter ended March 31, 2026. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934…

Principal Accounting Officer — Therese Abrams: Ms. Therese Abrams was promoted to Principal Accounting Officer.

Results of Operations and Financial Condition. On February 25, 2026, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the fourth quarter and year ended December 31, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities E…

Results of Operations and Financial Condition. On November 5, 2025, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the third quarter ended September 30, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Ac…

CFO — Geoffrey Porges: The filing confirms the separation of the Chief Financial Officer, a senior executive, which constitutes a genuine departure with high materiality.

Results of Operations and Financial Condition. On August 6, 2025, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the second quarter ended June 30, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1…

CFO — Richie Jain: The filing discloses the internal promotion of an existing senior executive to the role of Chief Financial Officer, which is a standard succession event rather than a departure.

Other Events. On May 19, 2025, Schrödinger, Inc. (the “Company”) restructured its operations to reduce its workforce and implemented focused cost reductions across the Company to improve the Company’s cash burn rate and enhance its operational efficiency. The reduction in workforce will decrease overall headcount by approximately 60 employees, which represents approximately 7% of full-time employees as of May 19, 2025. The Company estimates that it will incur approximately $3 million in charg…

Results of Operations and Financial Condition. On May 7, 2025, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the first quarter ended March 31, 2025. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934…

Results of Operations and Financial Condition. On February 26, 2025, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the fourth quarter and year ended December 31, 2024. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities E…

Results of Operations and Financial Condition. On November 12, 2024, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the third quarter ended September 30, 2024. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange A…

Entry into a Material Definitive Agreement. On November 11, 2024, Schrödinger, Inc. (the “Company”) entered into a research collaboration and license agreement (the “Agreement”) with Novartis Pharma AG (“Novartis”), pursuant to which, following expiration of the Hart-Scott-Rodino Act waiting period (the “Effective Date”), the Company and Novartis will collaborate on the discovery, research and pre-clinical development of small molecule compounds for targets in certain specified therapeutic ar…

Entry into a Material Definitive Agreement. On September 11, 2024 (the “Effective Date”), Schrödinger, LLC (“Schrödinger”), a wholly-owned subsidiary of Schrödinger, Inc. (the “Company”), entered into a Master License Agreement (the “Master License Agreement”) with The Trustees of Columbia University in the City of New York (“Columbia University”) that amended and restated Schrödinger’s existing license agreements with Columbia University, including (1) the Agreement, dated as of May 5, 1994,…

Results of Operations and Financial Condition. On July 31, 2024, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the second quarter ended June 30, 2024. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 19…

The filing discloses stockholder approval of amendments to equity incentive and stock purchase plans, which is a compensatory arrangement matter rather than a change in management or board composition.

Results of Operations and Financial Condition. On May 1, 2024, Schrödinger, Inc. (the “Company”) issued a press release announcing its financial results for the first quarter ended March 31, 2024. A copy of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated herein by reference. The information in this Form 8-K, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934…