of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission (the “SEC”), whether made before or after the date hereof, except as expressly set forth by specific refer…

Other Events. On May 18, 2026, Artivion completed its previously announced acquisition of Endospan pursuant to the exercise of Artivion’s option to purchase (directly or indirectly through an affiliate) all of the outstanding securities of Endospan. This transaction was consummated pursuant to that certain Securities Purchase Option Agreement, dated September 11, 2019, by and among Artivion, Endospan, the securityholders of Endospan listed in Schedule 1 thereto (together with any additional s…

Regulation FD Disclosure. On May 18, 2026, Artivion, Inc. (“Artivion”) issued a press release announcing the completion of the acquisition of Endospan Ltd. (“Endospan”), an Israeli corporation that designs, develops, markets and sells innovative products for the treatment of aortic instability, including the Nexus™ product. A copy of the press release is furnished as Exhibit 99.1 hereto. Such press release shall not be deemed “filed” for purposes of Section 18 of the Exchange Act of 1934, as…

Entry into a Material Definitive Agreement. Securities Purchase Option Agreement As previously disclosed in connection with the announcement of the Exclusive Distribution Agreement, dated September 11, 2019, between JOTEC GmbH, a wholly owned subsidiary of Artivion, Inc., a Delaware corporation formerly known as CryoLife, Inc. (“Artivion”), and Endospan Ltd., an Israeli corporation (“Endospan”), and the Loan Agreement and Debenture, each dated September 11, 2019 and amended on July 1, 2024, e…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission (the “SEC”), whether made before or after the date hereof, except as expressly set forth by specific refer…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

Entry into a Material Definitive Agreement. On September 26, 2025, Artivion, Inc. (the “Company”) entered into two Real Estate Purchase and Sale Contracts having substantially similar material terms, except as noted otherwise herein. The first agreement is between the Company and 1300 East Anderson Lane, Ltd. (the “1300 Seller”), a Texas limited partnership (the “1300 Purchase Agreement”). Pursuant to the 1300 Purchase Agreement, the 1300 Seller agreed to sell, and the Company agreed to purch…

Entry into a Material Definitive Agreement. On September 12, 2025 (the “Second Amendment Effective Date”), Artivion, Inc. (“Artivion”) entered into a Second Amendment to Credit and Guaranty Agreement (the “Amendment”), among Artivion, as borrower, certain subsidiaries of Artivion, as guarantors, the lenders party thereto and Ares Capital Corporation, as administrative agent, which amends the Credit and Guaranty Agreement dated as of January 18, 2024 (as amended from time to time prior to the…

Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. The information set forth under

Chief Medical Officer — Marshall S. Stanton: The filing discloses the planned retirement of the Chief Medical Officer effective March 2026, which is an orderly succession rather than a sudden loss, alongside an internal promotion of the CFO to COO.

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

Other Events. As previously announced, on May 14, 2025, Artivion, Inc. (the “Company”) entered into separate, privately negotiated exchange agreements with certain holders (the “Holders”) of the Company’s 4.250% Convertible Senior Notes due July 1, 2025 (the “Notes”). In addition, on May 22, 2025, the Company entered into an additional privately negotiated exchange agreement with a separate Holder (collectively, the “Exchange Agreements”). The transactions contemplated by the Exchange Agreeme…

Unregistered Sales of Equity Securities. The disclosure under

Other Events. On May 14, 2025, Artivion, Inc. (the “Company”) entered into separate, privately negotiated exchange agreements (the “Exchange Agreements”) with certain holders (the “Holders”) of the Company’s 4.250% Convertible Senior Notes due July 1, 2025 (the “Notes”). Under the terms of the Exchange Agreements, the Holders agreed to exchange an aggregate principal amount of approximately $94.54 million of Notes held by the Holders in exchange for an aggregate number of shares of the Compan…

Unregistered Sales of Equity Securities. The disclosure under

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

Other Events On December 23, 2024, in accordance with the Indenture (the “Indenture”) dated June 23, 2020, between Artivion, Inc. (formerly CryoLife, Inc.) (the “Company”) and U.S. Bank Trust Company, National Association, as Trustee, relating to the Company’s 4.250% Convertible Senior Notes due 2025 (the “Notes”), the Company gave notice to the Trustee, the Conversion Agent, and the Holders (each as defined in the Indenture) that the Company elected to change the “Default Settlement Method”…

Other Events Artivion, Inc. (“Artivion” or the “Company”) identified and began taking measures to address a cybersecurity incident on November 21, 2024. Artivion’s response measures included taking certain systems offline, initiating an investigation, and engaging external advisors, including legal, cybersecurity, and forensics professionals to assess, contain, and remediate the incident. The incident involved the acquisition and encryption of files. The Company is working to securely restore…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…

Entry into a Material Definitive Agreement Amended and Restated Loan Agreement & Amended and Restated Debenture Artivion, Inc. (the “Company”) previously entered into a Loan Agreement and Debenture with Endospan Ltd. (“Endospan”), dated September 11, 2019, pursuant to which the Company provided Endospan a secured loan in an amount of $15 million. The Company and Endospan entered into an Amended and Restated Loan Agreement dated July 1, 2024 and, in connection therewith, entered into an Amende…

of Form 8-K and shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that Section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, nor shall it be deemed incorporated by reference into any of Artivion’s reports or filings with the Securities and Exchange Commission, whether made before or after the date hereof, except as expressly set forth by specific reference in such…