and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

Termination of a Material Definitive Agreement. On August 14, 2026, the Second Amendment became effective and replaced the Prior Agreement, which effectively terminated the Prior Agreement, as described in

Entry into a Material Definitive Agreement. On August 14, 2026, Renergen Limited (the “Borrower”), a wholly-owned subsidiary of ASP Isotopes Inc. (the “Company”), entered into a Second Amendment and Restatement Agreement (the “Second Amendment”) with The Standard Bank of South Africa Limited (the “Lender”). Capitalized terms which are not defined herein shall have the meanings ascribed to such terms in the Second Amendment. The Second Amendment replaced the Amended and Restated Secured Term L…

Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant. On August 14, 2026, the Second Amendment became effective. The terms of the Second Amendment are described in

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

Results of Operations and Financial Condition. On August 4, 2026, ASP Isotopes Inc. (the “Company”) issued a letter to shareholders, which is attached hereto as Exhibit 99.1 and is incorporated by reference herein (the “Shareholder Letter”). The information furnished pursuant to this Item 2.02, including Exhibit 99.1, shall not be deemed to be “filed” for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and will not be incorporated by referen…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

Entry into a Material Definitive Agreement. On July 15, 2026, ASP Isotopes Inc. (the “Company”) and Quantum Leap Energy LLC (“QLE”), a subsidiary of the Company, entered into separate, individually negotiated private exchange agreements (collectively, the “Exchange Agreements”) with certain holders of QLE’s outstanding 8.0% Convertible Promissory Notes due November 19, 2030 (the “QLE Notes”) to exchange approximately $109.2 million aggregate principal amount of the Notes (the “Exchanged Notes…

Unregistered Sales of Equity Securities. The information contained in

Regulation FD Disclosure. On June 25, 2026, ASP Isotopes Inc. (the “Company”) and ENDRA Life Sciences Inc. (“ENDRA”) issued a joint press release announcing the proposed merger of Noble Africa LLC (“Noble Africa”), a wholly-owned subsidiary of the Company and an intermediate holding company for Renergen Limited, with a subsidiary of ENDRA, with Noble Africa continuing as the surviving entity, and that Noble Africa has entered into subscription agreements with certain accredited investors, qua…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

Regulation FD Disclosure. On May 26, 2026, ASP Isotopes Inc. (the “Company”) issued a press release regarding the Company's production of Silicon-28, which is attached hereto as Exhibit 99.1 (the “Press Release”) and is incorporated by reference herein. In addition, the Company released its latest investor presentation (the “Presentation”). The Presentation is available on the Company’s website, www.aspisotopes.com, on the Home page. All of the information in the Press Release and the Present…

Regulation FD Disclosure. On May 20, 2026, ASP Isotopes Inc. (the “Company”) released its latest investor presentation (the “Presentation”). The Presentation is available on the Company’s website, www.aspisotopes.com, on the Home page. All of the information in the Presentation is presented as of the date hereof, and the Company does not assume any obligation to update such information in the future. The information in the Presentation shall not be deemed to be “filed” for purposes of Section…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release, the Business Update Call Presentation and the Corporate Overview shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date here…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…

and in the Press Release shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended, and shall not be incorporated by reference into any filing with the U.S. Securities and Exchange Commission, whether made by the Company before or after the date hereof, regardless of any general incorporation language in such filin…