Alnylam Pharmaceuticals, Inc. (ALNY)
NASDAQHealth CareBiotechnologySnapshot 2026-09-04
$266.11+0.61%
Close 2026-09-04 · 1-day change
NASDAQHealth CareBiotechnologySnapshot 2026-09-04
Research Workspace
Put ALNY beside peers and holdings, graph the same metric, and keep your notes with the evidence.
Daily closes. Earnings/event dots are placed inline.
Industries move in repeating boom-and-bust cycles. This shows where this stock’s industry sits in that cycle, stage by stage (recovery → expansion → supercycle → steady → deceleration → contraction), from its fundamentals (orders, revenue, capital spending), not the stock’s price.
A booming industry is a tailwind for the names in it; a contracting one is a headwind. Companies in the same industry tend to rise and fall together with the cycle, the way a tide lifts and lowers every boat in the harbor at once, so a large part of a stock’s swing can come from where its industry sits rather than from the company itself. It’s context for reading the company’s results, not a buy/sell call. Full explanation →
Biotechnology is in expansion. Describes the industry's cycle state, not a call on this stock.
The stage band shows the industry’s cycle over the chart’s timeline (each color a stage); a ▼ marks a quarter its growth inflected down — amber is an unconfirmed watch, red is confirmed the next quarter. Use “Overlay cycle on chart” to tint the price chart by stage. The industry’s fundamentals, not a signal on this stock.
Primary pillar broken — Achieve $4.9B-$5.3B revenue in 2026: FY26 revenue guidance $4.2B-$4.5B vs $4.9B-$5.3B target.
View ThesisRevenue growth is accelerating — up about 95% over the past year.
View GrowthMiddle-of-the-pack quality for its industry.
View QualityManagement screens strong on capital allocation, margins, market reaction to earnings.
View ManagementExpectations look reasonable — what the market is pricing in sits in line with or below what analysts forecast.
View ValuationThis stock is volatile — it swings about 2% on a typical day and fell roughly 58% in its worst 12-month stretch.
View RiskAlnylam's growth relies on expanding TTR franchise revenues to $4.2B-$4.5B in 2026. Revenue grew 67% year over year, and the last quarter beat expectations. It trades at 36× P/E versus a 22× peer median, indicating the price reflects less growth than forecast. The primary risk is the guidance cut, which lowered revenue expectations to $4.2B-$4.5B from $4.9B-$5.3B. Peer multiples imply a price about 5% below where it trades. This read is provisional.
Trailing returns as of 2026-09-04. ALNY is total return (includes dividends); the S&P 500 benchmark is price return (the index excludes dividends).
Based on 30 analysts currently covering ALNY (as of Sep 2026).
Based on 12 Wall Street analysts offering 12-month price targets for ALNY in the last 4 months.
Continue this research
Compare ALNY with peers and holdings, graph the same reported metric, keep your questions beside the evidence, and return when the facts change.
Free account required to save the handoff. No credit card.
| Compare | Company | Living FV | P/E | Revenue % | Quality |
|---|---|---|---|---|---|
| ALNY Selected company | Graph | Compare | Trend | Review | |
| Peer Add a competitor | Graph | Compare | Trend | Review | |
| Holding Compare a holding | Graph | Compare | Trend | Review |
Selected metric trend
Quarterly · checked companies · value or % of revenue
A consensus fair price across 7 valuation methods, at three horizons. As of 2026-09-04. Estimates are diagnostics, not price targets. Short-horizon estimates are close to coin-flips, so confidence is a method-agreement read, not a prediction.
Today's peer multiple on trailing earnings, with no growth credited. This is the headline read.
Adds projected growth, so it leans optimistic by design. Read it as upside context, not a base case.
A price-focused, side-by-side fair-value read versus Biotechnology — fair value, gap to price, and forward P/E.
Compare the value case
Put ALNY next to peers and holdings, compare Living FV and multiples, then graph the driver behind the difference.
Advances: Expand TTR Franchise revenues to $4.2B-$4.5B in 2026
Not investment advice. Scores describe historical and current data; they are not forecasts of future returns. Consult a licensed advisor before making investment decisions.
End-of-day figures as of 2026-09-04. EPS is implied from price ÷ P/E. Not investment advice.
Current $266.11
The last 12 months of price, then the range of analyst 12-month targets from today’s $266.11.
Analyst ratings and price targets are third-party Wall Street estimates, not QuarterlyIQ’s view. Not investment advice.
A long-thesis check that carries the widest uncertainty of the three horizons.
Around the middle on quality vs scored peers
Direction of the business behind the multiple. Bands are backend reads; trailing-12-month basis.
Supports revenue growth for TTR franchise across patient groups.
Threatens: Achieve $4.9B-$5.3B revenue in 2026
Concerns over silencer drug could impact revenue projections.
Advances: Expand TTR Franchise revenues to $4.2B-$4.5B in 2026
Positive data supports TTR franchise revenue growth.
Threatens: Expand TTR Franchise revenues to $2.475B-$2.525B
Guidance cut raises concerns about revenue growth.
Advances: Achieve $4.9B-$5.3B revenue in 2026
Forecasting higher revenue supports growth objectives.
Advances: Expand TTR Franchise revenues to $2.475B-$2.525B
Commercial momentum supports TTR franchise revenue growth.
Threatens: Expand TTR Franchise revenues to $2.475B-$2.525B
Price target cut reflects concerns about TTR Franchise growth.
Rival trial failure may impact market dynamics and competitive landscape.